FIELD: organic chemistry, antiviral agents.
SUBSTANCE: invention relates to a method for synthesis of β-L-5-fluoro-2',3'-dideoxy-2',3'-didehydrocytidine (β-L-FD4C) that is used as an antiviral agent. This method can be used in the large-scale manufacture of β-L-FD4C and it displays the effectiveness, high economy and ecology acceptable.
EFFECT: improved method of synthesis.
23 cl, 1 tbl, 1 ex
| Title |
Year |
Author |
Number |
| SYNTHESIS OF β-L-2'-DESOXYNUCLEOSIDES |
2004 |
- Storer Richard
- Mussa Adel'
- Van Tszin Jan
- Chaudkhuri Narajan
- Mat'E Stiven
- Stjuart Alistehr
|
RU2361875C2 |
| METHOD OF PRODUCING 1,3-OXATHIOLANE NUCLEOSIDES |
1999 |
- Pehjnter Dzhordzh R.
- Liotta Dennis K.
- Ehlmond Merrik
- Kliri Dehrril
- Sorija Khose
- Shnajdman Markos Luis
|
RU2439069C2 |
| METHOD FOR PREPARING 1,3-OXATHIOLAN NUCLEOSIDE, METHOD FOR PREPARING DERIVATIVE OF 1,3-OXATHIOLANYL-5-ONE |
1999 |
- Pehjnter Dzhordzh R.
- Liotta Dennis K.
- Ehlmond Merrik
- Kliri Dehrril
- Sorija Khose
- Shnajdman Markos Luis
|
RU2244712C2 |
| β-L-2' DEOXY-NUCLEOSIDES FOR TREATING HEPATITIS B |
1999 |
- Gosselehn Zhill'
- Imbak Zhan-Lui
- Brajant Martin L.
|
RU2424016C2 |
| METHOD OF SYNTHESIS OF 2',3'-DIDEOXY-3'-THIACYTYDINE OR 2',3'- -DIDEOXY-3'-THIA-5-FLUOROCYTIDINE, NUCLEOSIDE ENRICHED WITH ENANTIOMER, METHOD OF SYNTHESIS OF 1,3-OXATHIOLANE, METHOD OF SYNTHESIS OF 2-ACYLOXY-5-ACYLOXY-1,3-OXATHIOLANE ENRICHED WITH ENANTIOMER, ENANTIOMERS, METHOD OF CLEAVAGE OF NUCLEOSIDE ENANTIOMERS |
1991 |
- Lajott Dennis Ts
- Choj Vu-Big
|
RU2125558C1 |
| MONOCYCLIC L-NUCLEOSIDES, THEIR ANALOGUES AND USING |
1997 |
- Ramasejmi Kandasejmi
- Tehm Robert
- Ehverett Devron
|
RU2188828C2 |
| METHOD FOR PREPARING BENZOPYRAN-2-OL DERIVATIVES |
2007 |
- Akhman Jens Bertil'
- Dillon Barri Richard
- Pettman Alan Dzhon
|
RU2397163C2 |
| CIS-N-IMINOMETHYL-3,4-DISUBSTITUTED-β-LACTAMS AND METHODS OF PREPARING CIS-3,4-DISUBSTITUTED-β-LACTAMS, AND USE THEREOF |
1994 |
- Allan V.Rehj
- Parashotam Vemishetti
- Roberto Drogini
|
RU2132844C1 |
| NEW METHOD OF SYNTHESIS OF N-ACETYL-(L)-4-CYANOPHENYLALANINE, AC-(L)-PHE-(4-CN)-OH, AND N-ACETYL-(L)-PARA-AMIDINOPHENYL- -ALANINE-CYCLOHEXYLGLYCINE-β-(3-N- METHYLPYRIDINIUM)-ALANINE, AC-(L)-PAPH-CHG-PAL-ME-(3)-β |
1996 |
|
RU2170764C2 |
| SYNTHESIS OF 3-AMINO-3-ARYLPROPANOATES |
2000 |
- Abdel'-Magid Akhmed F.
- Kokhen Judit Kh.
- Mar'Janoff Sintija A.
- Villani Frehnk Dzhon Ml.
- Zong Khua M.
|
RU2225859C2 |
