METHOD OF RESTORING MANDIBULAR BONE TISSUE AFTER CISTECTOMY OPERATION Russian patent published in 2007 - IPC A61K31/722 A61K31/726 A61K31/727 A61K31/728 A61K38/30 A61P1/02 

FIELD: stomatology.

SUBSTANCE: cistectomy comprises resection of fang apexes followed by instrumental and medicaments treatment of osseous cavity. Then osseous cavity is filled with osteoplastic material containing 2% chitosan ascorbate having molecular weight 100-700 kDa and degree of deacetylation 95-98% including, based on 1 g dry chitosan ascorbate: 5-100 mg chondroitinsulfuric acid, 10-100 mg hyaluronic acid, 2.5-5 mg heparin, 11-220 μg bovine serum growth factor, and 4% sodium alginate at chitosan-to-sodium alginate ratio 1:1.

EFFECT: shortened bone tissue restoration time and prevented postoperation complications due to better compatibility of utilized osteoplastic material with bone tissue and lack of allergenic activity in this material.

5 dwg, 2 ex