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2 311 459

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IPC

C12N15/72(2006-01-01)

C12N15/12(2006-01-01)

(21) (22)

Application

2005135233/13, 2005-11-14

(24)

Start date

2005-11-14

(22)

Actual filing date

2005-11-14

(45)

Published

2007-11-27

(72)

Inventor

Rjabchenko Aleksandr VladimirovichLavrinenko Igor' AlekseevichBeklemishev Anatolij Borisovich

(73)

Holder

Gosudarstvennoe Uchrezhdenie Nauchno-Issledovatel'Skij Institut Biokhimii Sibirskogo Otdelenija Rossijskoj Akademii Meditsinskikh Nauk Nii Biokhimii So Ramn)

RECOMBINANT PLASMID DNA FOR DETECTION OF AGENTS DAMAGING GENETIC APPARATUS OF CELL (VARIANTS) Russian patent published in 2007 - IPC C12N15/72 C12N15/12

Abstract RU 2311459 C2

FIELD: biotechnology, molecular biology.

SUBSTANCE: invention proposes a recombinant plasmid DNA providing synthesis of fluorescent mutant protein GFR from Aequorea Victoria in Rec⁺ strains of E. coli under control of regulatory region of recA gene from Proteus mirabilis. Invention provides the enhanced sensitivity of some factors of chemical nature damaging DNA and damaging factors of physical nature also. Invention can be used food processing, pharmaceutical and chemical industry.

EFFECT: valuable biological properties of plasmid DNA.

2 cl, 12 dwg, 2 ex

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RU 2 311 459 C2

Authors

Rjabchenko Aleksandr Vladimirovich

Lavrinenko Igor' Alekseevich

Beklemishev Anatolij Borisovich

Dates

2007-11-27—Published

2005-11-14—Filed