FIELD: biotechnology, medicine, allergology.
SUBSTANCE: invention proposes a transformed cell of lactobacillus microorganism. Cell expresses surface polypeptide that comprises peptide sequence mimicking part of conformational epitope of IgE molecule. Surface polypeptide is represented by protease from L. bulgaricus anchored on cellular surface. Also, invention proposes a nutrient composition and pharmaceutical composition containing such cell. Proposed invention can be used in treatment of allergy and/or prophylaxis of symptoms of allergic responses.
EFFECT: valuable medicinal properties of microorganism.
11 cl, 3 dwg, 6 ex
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