FIELD: virology, biotechnology, medicine, biochemistry.
SUBSTANCE: invention relates to creature agents used in AIDS treatment. Invention proposes pentapeptide of the following structure: Tyr-Pro-Ile-Glu-MeHis of molecular mass 672 Da. Peptide is prepared from sea worm Polychaeta, Eunicidae viscera homogenate extract. Method involves the successive purification by hydrophobic chromatography and reversed-phase high-performance liquid chromatography. Invention expands assortment of natural non-nucleoside inhibitors of HIV reverse transcriptase.
EFFECT: valuable medicinal properties of agent.
3 tbl, 10 dwg
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