SINGLE-USE DEVICE FOR REVEALING ANTIGEN-TARGET IN LIQUID SAMPLE AND METHOD OF MEASURING AMOUNT OF ANTIGEN-TARGET IN LIQUID SAMPLE Russian patent published in 2008 - IPC G01N33/543 

FIELD: medicine; methods of diagnostics.

SUBSTANCE: device for revealing antigen-target in liquid sample has reaction chamber; immobilized antibody fixed inside reaction chamber; complex-reporter provided with probe and antigen of complex-reporter, where probe is connected with antigen of complex-reporter. Antigen of complex-reporter is connected with immobilized body. Antigen of complex-reporter is connected with antigen-target less tight than antigen-target. Device has revealing chamber, input for entering reaction chamber and passage for sample between reaction chamber and revealing chamber. When part of antigen of complex-reporter dissociates from immobilized body to liquid sample, antigen-target binds with immobilized body. When liquid sample is transferred to revealing chamber, amount of complex-reporter is found, which amount has to be indicator of quantity of antigen-target that quantity was presented in liquid sample initially. Described device has to be single-use immune sensor, which doesn't need to be washed through. There are no requirements to user concerning stages of measurement. Sensor can be easily adapted to antigen-antibody interactions within wide kinetic limits. Availability or absence of antigen in sample can found precisely.

EFFECT: improved precision of measurement.

42 cl, 4 dwg