FIELD: organic chemistry, medicine, pharmacy.
SUBSTANCE: invention relates to a novel compound of the general formula (I): wherein R means hydrogen atom (H), -OH, carbamoyl group; n = 1 or 2, or to its pharmaceutically acceptable salt. Compounds of the formula (I) are potential inhibitors of cellular adhesion mediated by integrins that allows its using as components of pharmaceutical composition used in treatment or prophylaxis of inflammatory, autoimmune or allergic state or rejection mediated by LFA-1.
EFFECT: valuable medicinal properties of compound and pharmaceutical composition.
19 cl, 2 sch, 3 dwg, 3 tbl, 7 ex
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Authors
Dates
2008-01-27—Published
2003-02-06—Filed