AMIDES OF DIASABICYCLOALKANES, SELECTIVE WITH RESPECT TO ACETYLCHOLINE SUBTYPE OF NICOTINIC RECEPTORS Russian patent published in 2014 - IPC C07D471/08 A61K31/549 A61P25/00 A61P25/08 

FIELD: medicine, pharmaceutics.

SUBSTANCE: claimed invention relates to novel compounds of formula I: where n has values 0 or 1, and Cy represents a heteroaryl group, selected from such groups as 2-furanyl, 3-furanyl, 2-oxazolyl, 4-oxazolyl, 5-oxazolyl, 3-isoxazolyl, 4-isoxazolyl, 5-isoxazolyl and 4-pyridinyl, where heteroaryl groups are optionally substituted by up to 3 substituents, different from hydrogen, independently selected from C_1-6alkyl, C_2-6alkenyl, C_2-6alkinyl, C_3-8cycloalkyl, substituted phenyl, furyl, halogen, -OR', -CF₃, -CN, -NO₂, -SO₂R', -SO₂NR'R″, -R'SO₂R″, where R' and R″ are independently selected from hydrogen, C_1-6alkyl, where the term "substituted", applicable with respect to substituted phenyl, relates to substitution with one or several halogens, and their pharmaceutically acceptable salts, as well as to pharmaceutical compositions based on the said compounds.

EFFECT: application of the said compounds for treatment and/or prevention of wide spectrum of CNS diseases and disorders.

13 cl, 2 dwg, 1 tbl, 11 ex