FIELD: organic chemistry, medicine, pharmacy.
SUBSTANCE: invention relates to drugs and in particular provides a receptor ligand activated by peroxisome proliferator γ (PPAR γ), and a composition comprising the indicated ligand used for aim in improving insulin-resistance state or for prevention and/or improving the insulin-resistance syndrome state. Invention relates to a receptor ligand activated by peroxisome proliferator that comprises prenylflavonoid, chalcone derivative, flavonol derivative and their salt, glycoside and/or esterified form. Also, invention relates to composition comprising abovementioned ligand, a vegetable extract containing abovementioned ligand, and to a novel compound (dehydroglyasperin D) represented by the following formula: 
.
EFFECT: improved preparing method, valuable medicinal properties of ligand.
33 cl, 26 tbl, 13 ex
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