FIELD: immunology.
SUBSTANCE: invention relates to immune compositions and vaccines used in treatment and prophylaxis of neusserial disease. Immune compositions comprise combinations of antigens chosen from at least two different classes of antigens and comprising adhesions, auto-transporting proteins, toxins, proteins taking part in assimilation of iron and membrane-associated proteins (preferably integral protein(s) of external membrane). Such combinations of antigens are able to target the immune response against different aspects of Neusseria vital cycle that results to the more effective immune response.
EFFECT: valuable medicinal properties of vaccine compositions.
86 cl, 1 tbl, 10 dwg, 21 ex
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