FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to immunology, and concerns preparing meningococcal vaccines. What is presented is a kit for preparing an immunogenic composition for serogroup B Neisseria meningitidis containing: (i) a first containing comprising an adjuvant containing an oil-in-water emulsion; and (ii) a second containing comprising a lyophilised antigenic composition containing an immunogen for inducing the immune response to serotype B Neisseria meningitidis. The lyophilized antigens Men-B may be reduced into an adjuvant form ready for administration into the patient at the moment of use. The lyophilised component may also contain one or more conjugated saccharides of serogroup A, C, W135 and/or Y N. meningitides.
EFFECT: invention enables preparing the storage-stable and effective compositions.
7 cl, 3 dwg
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