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2 318 555

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(51)

IPC

A61N5/10(2006-01-01)

(21) (22)

Application

2006130605/14, 2006-08-24

(24)

Start date

2006-08-24

(22)

Actual filing date

2006-08-24

(45)

Published

2008-03-10

(72)

Inventor

Mitel'Man Ljudmila Jul'EvnaKurilov Konstantin SemenovichKuznetsova Tat'Jana Alekseevna

(73)

Holder

Mitel'Man Ljudmila Jul'EvnaKurilov Konstantin SemenovichKuznetsova Tat'Jana Alekseevna

METHOD FOR APPLYING RADIATION IN CARRYING OUT COMBINED TREATMENT OF GASTROINTESTINAL TRACT MALIGNANT NEOPLASM PATIENTS Russian patent published in 2008 - IPC A61N5/10

Abstract RU 2318555 C1

FIELD: medicine.

SUBSTANCE: method involves applying intraoperative radiation therapy IORT with remote gamma-therapy RGT being added after pause with tissue irradiation being under control when planning IORT and RGT combinations, based on TDF factor values. Single IORT dose is judged to be equal to 10-15 Gy and it is complemented with RGT total focal dose of 30-40 Gy. TDF factor value is calculated from formula where D_s is the single IORT dose, Gy; X_s is the time interval between IORT and RGT, days; D_f,i is the single RGT dose, Gy; X_f,i is the time interval between RGT sessions, days; K_s =(S/100)^0.37 is the irradiation field area, cm².

EFFECT: enabled operation within therapeutic dose boundaries; reduced risk of late radiation injuries; accelerated treatment course.

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RU 2 318 555 C1

Authors

Mitel'Man Ljudmila Jul'Evna

Kurilov Konstantin Semenovich

Kuznetsova Tat'Jana Alekseevna

Dates

2008-03-10—Published

2006-08-24—Filed