FIELD: medicine.
SUBSTANCE: invention concerns medicine, particularly oncology, and can be applied in treatment of mammary gland cancer. Method involves mammary gland resection and radiation therapy at post-operation stage. Intraoperation radiation therapy (IORT) is performed at tumour bed in amount of 10 Gy. For that purpose, radiation area is formed after resection by wound edge constriction with ligature. Then induction accelerator collimator matching resection size is installed in wound. Upper wound edges are attached to lower collimator part, so that radiation area does not include skin and adjoining subcutaneous cellular tissues. Then radiation is performed, followed by axillary lymphadenectomy through the same operation access during radical resection. Wounds are sutured with drainage remaining in axillary area and transplant bed area. 2 chemotherapy courses are performed over two weeks upon prescription, followed by remote gamma therapy (RGT) over 2-4 weeks in standard dosage fractioning mode, the number of sessions defined by formula: N=12.6(2.4-Xu -0.169), where N is required number of remore gamma therapy sessions; Xu is time interval, days, between IORT and RGT sessions' radiation therapy is followed by 2-4 chemotherapy sessions, if required by prescription.
EFFECT: preservation of cosmetic result for plastic reconstruction operations for mammary gland cancer patients, prolonged term of survival without recurrences.
1 ex, 7 dwg
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Authors
Dates
2009-03-20—Published
2007-07-30—Filed