FIELD: organic chemistry, medicine, oncology, pharmacy.
SUBSTANCE: invention relates to nonhygroscopic crystalline 5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-morpholin-4-ylpropyl]-2,2-dimethyl-1H-pyrrol-3-carboxamide maleate salt that possesses inhibitory effect on tyrosine kinase receptors. Also, invention relates to a pharmaceutical composition and to a method for treatment of cancer in mammals using such compositions.
EFFECT: valuable medicinal property of compound and pharmaceutical composition.
12 cl, 12 tbl, 17 dwg, 5 ex
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Year |
Author |
Number |
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|
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|
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