BIOADHESIVE SYSTEM FOR DELIVERING MEDICINAL PREPARATIONS Russian patent published in 2008 - IPC A61K9/107 A61P15/00 A61F6/06 

FIELD: medicine.

SUBSTANCE: the present innovation deals with the systems of vaginal delivery of medicinal preparations at practically neutral pH value that include: emulsion at practically neutral pH value that contain globules, being of two phases: internal water-soluble phase and external water-insoluble phase or a film that contain a therapeutically active preparation or preparations, moreover, acid buffered phase contains a therapeutically active preparation or preparations independently or in combination with additional buffer substance; moreover, acid buffered phase could be isotonic, hypertonic or hypotonic. New systems provide the chance to deliver therapeutically active preparation due to modified method intravaginally for prolonged period of time, up until 168 h. The systems mentioned could take the form of multi-phase liquid or semi-solid substance to be easily introduced into vaginal cavity at no active leakage from there.

EFFECT: higher efficiency.

57 cl, 2 ex, 2 tbl