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2 320 351

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IPC

A61K33/06(2006-01-01)

A61K33/10(2006-01-01)

A61K33/14(2006-01-01)

A61K31/7004(2006-01-01)

A61K35/14(2006-01-01)

A61P9/00(2006-01-01)

(21) (22)

Application

2004131315/15, 2004-10-25

(24)

Start date

2004-10-25

(22)

Actual filing date

2004-10-25

(45)

Published

2008-03-27

(72)

Inventor

Khubulava Gennadij Grigor'EvichZhuravlev Valerij PetrovichBirjukov Andrej Valer'EvichRomanovskij Dmitrij Jur'Evich

(73)

Holder

Voenno-Meditsinskaja Akademija Im. S.M. Kirova

CARDIOPLEGIC SOLUTION FOR INTRAOPERATION PROTECTION OF MYOCARDIUM Russian patent published in 2008 - IPC A61K33/06 A61K33/10 A61K33/14 A61K31/7004 A61K35/14 A61P9/00

Abstract RU 2320351 C2

FIELD: medicine, chemical-pharmaceutical industry, pharmacy.

SUBSTANCE: invention relates to cardiosurgery and can be used in operations on heart. Invention proposes a cardioplegic solution for intraoperation protection of myocardium containing the following components, ml: 5% KCl solution, 11-14; 5% NaHCO₃ solution, 4-6; 25% MgSO₄ solution, 1-2; 15% mannitol solution, 12-15; 40% glucose solution, 0.5-2; 10% calcium gluconate solution, 1-2, and 0.9% NaCl solution up to 100 ml Prepared solution is mixed with autoblood in the ratio 1:4. The claimed invention allows decreasing dose of inotropic support in post-operation period and to reduce possibility of negative results after operation on heart.

EFFECT: valuable medicinal properties of solution.

1 tbl

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RU 2 320 351 C2

Authors

Khubulava Gennadij Grigor'Evich

Zhuravlev Valerij Petrovich

Birjukov Andrej Valer'Evich

Romanovskij Dmitrij Jur'Evich

Dates

2008-03-27—Published

2004-10-25—Filed