FIELD: organic chemistry, medicine, pharmacy.
SUBSTANCE: invention relates to novel pharmaceutically acceptable topiramate salts: crystalline topiramate sodium salt of the formula (II): 
characterized by roentgenograms Na1 and Na2, and crystalline topiramate potassium salt of the formula (III): 
characterized by roentgenograms K1 and K2. These compounds possess anticonvulsant effect and used in epilepsy treatment. Also, invention relates to pharmaceutical composition based on thereof and to a method for their preparing.
EFFECT: valuable medicinal properties of compounds and pharmaceutical compositions.
4 cl, 10 tbl, 22 ex
| Title | Year | Author | Number |
|---|---|---|---|
| NEW SALTS OF ANTICONVULSANT COMPOUNDS | 2003 |
|
RU2330041C2 |
| METHOD OF PRODUCING A THIAZOLE DERIVATIVE | 2016 |
|
RU2738937C2 |
| METHOD OF PRODUCING CHIRAL TRIAZOLONES | 2011 |
|
RU2585760C2 |
| METHOD FOR PRODUCING 2-[(3R)-3-METHYLMORPHOLIN-4-YL]-4-(1-METHYL-1H-PYRAZOL-5-YL)-8-(1H-PYRAZOL-5-YL)-1,7-NAFTHYRIDINE | 2019 |
|
RU2802512C2 |
| METHODS FOR PREPARING SUBSTITUTED ARYL-CONDENSED AZAPOLYCYCLIC COMPOUNDS, INTERMEDIATE SUBSTANCES AND METHODS FOR THEIR PREPARING | 2002 |
|
RU2282619C9 |
| PSEUDOFRUCTOPYRANOSE SULFAMATES AND PHARMACEUTICAL COMPOSITION BASED ON SAID | 1994 |
|
RU2139875C1 |
| METHOD OF BIPHENYLIMIDAZOLE COMPOUNDS | 2010 |
|
RU2552350C2 |
| BENZOXAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITION HAVING PROPERTIES OF ADENOSINE RECEPTOR LIGANDS | 2004 |
|
RU2334742C2 |
| SYNTHESIS OF N-(4-FLUOROBENZYL)-N-(1-METHYLPIPERIDIN-4-YL)-N'-(4-(2-METHYLPROPYLOXY)PHENYLMETHYL)CARBAMIDE, AS WELL AS TARTRATE AND CRYSTALLINE FORMS THEREOF | 2005 |
|
RU2417986C2 |
| AZA-ADAMANTANE DERIVATIVE MONOHYDRATE | 2011 |
|
RU2579121C2 |
