FIELD: medicine.
SUBSTANCE: method involves simultaneously evaporating raw organic drug substance and auxiliary surfactant in gas medium under rarefaction of 7.51-0.0375 Pa. The so produced drug and auxiliary surfactant vapors are cocondensed on sedimentation surface. When cocondensing the ingredients vapor sedimentation velocity vectors of the organic drug and auxiliary surfactant vapors are directed towards the sedimentation surface center. Angle between the vapor sedimentation velocity vectors of the organic drug and auxiliary surfactant and inclination angle of angle bisector to the sedimentation surface is equal to 5-170° and 10-90°. Microcapsulating process is carried out at positive sedimentation surface temperature in cocondensation process or in heating process for reaching positive temperatures of the produced cocondensate under negative sedimentation surface temperature.
EFFECT: single-stage microcapsulated drugs production.
2 cl, 15 dwg
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Authors
Dates
2008-04-10—Published
2006-09-05—Filed