Patenton — panteon of patents

(19)

RU

(11)

2 321 628

(13)

C1

(51)

IPC

C12N1/21(2006-01-01)

C12P21/00(2006-01-01)

C12R1/07(2006-01-01)

(21) (22)

Application

2006122787/13, 2006-06-26

(24)

Start date

2006-06-26

(22)

Actual filing date

2006-06-26

(45)

Published

2008-04-10

(72)

Inventor

Mikshis Natal'Ja IvanovnaPopov Jurij AlekseevichKudrjavtseva Ol'Ga Mikhajlovna

(73)

Holder

Federal'Noe Gosudarstvennoe Uchrezhdenie Zdravookhranenija Nauchno-Issledovatel'Skij Protivochumnyj Institut Federal'Noj Sluzhby Po Nadzoru V Sfere Zashchity Prav Potrebitelej I Blagopoluchija Cheloveka

RECOMBINANT STRAIN Bacillus anthracis STIΔTPA-1 (pUB110PA-1) AS PRODUCER OF ANTHRAX MICROORGANISM ANTIGEN Russian patent published in 2008 - IPC C12N1/21 C12P21/00 C12R1/07 

Abstract RU 2321628 C1

FIELD: biotechnology, microbiology.

SUBSTANCE: invention proposes the recombinant strain B. anthrax STIΔTPA-1 (pUB110PA-1) that produces the anthrax microorganism protective antigen. The strain is obtained by transformation of the strain B. anthrax STIΔT with hybrid plasmid pUB110PA-1 DNA and deposited in GK of pathogenic microorganisms "Mikrob" at number KM-96. The strain is characterized by stability of hybrid replicon and high level of production of the protective antigen representing the main component of chemical anthrax vaccines, and safety in using.

EFFECT: valuable biological properties of strain.

8 ex

Similar patents RU2321628C1

Title Year Author Number
ASPOROGENOUS RECOMBINANT STRAIN Bacillus anthracis 55ΔТПА-1Sро (pUB110РА-1) AS PRODUCER OF ANTHRAX MICROORGANISM ANTIGEN 2006
  • Mikshis Natal'Ja Ivanovna
  • Popov Jurij Alekseevich
  • Shulepov Dmitrij Viktorovich
 RU2321629C1
METHOD OF PRODUCTION OF PROTECTIVE ANTIGEN AND PROTEIN OF S-LAYER EA1OF ASPOROGENOUS RECOMBINANT STRAIN IN anthracis 55 ΔTPA-1Spo 2012
  • Mikshis Natal'Ja Ivanovna
  • Goncharova Anastasija Jur'Evna
  • Popova Polina Jur'Evna
  • Kudrjavtseva Ol'Ga Mikhajlovna
  • Popov Jurij Alekseevich
  • Kutyrev Vladimir Viktorovich
 RU2492241C1
DNA-STRUCTURE ENCODING MODIFIED VERSION OF PROTECTIVE ANTIGENE BACILLUS ANTHRACIS 2015
  • Letarov Andrej Viktorovich
  • Epova Ekaterina Yurevna
  • Kulikov Evgenij Evgenevich
  • Golomidova Alla Konstantinovna
  • Ivanov Pavel Aleksandrovich
  • Trifan Valerij Nikandrovich
  • Melnik Nikolaj Vasilevich
  • Lajpanov Boris Kazievich
  • Belyakova Alla Vladimirovna
  • Leonovich Oksana Aleksandrovna
  • Biryukova Yuliya Konstantinovna
  • Zylkova Marina Valerevna
  • Samujlenko Anatolij Yakovlevich
 RU2622085C2
E. COLI STRAIN - PRODUCER OF ISOLATED DOMAIN 1 OF PROTECTIVE BACILLUS ANTHRACIS ANTIGEN IN FORM OF VIRUS-LIKE PARTICLES 2016
  • Shibaeva Anna Valerevna
  • Letarov Andrej Viktorovich
  • Kulikov Evgenij Evgenevich
  • Golomidova Alla Konstantinovna
  • Pozdnyakova Natalya Vladimirovna
  • Kuznetsova Tatyana Vladimirovna
  • Smirnova Mariya Sergeevna
  • Lebedeva Anna Aleksandrovna
  • Biryukova Yuliya Konstantinovna
 RU2633508C1
STRAIN BACILLUS ANTHRACIS KM92 AS PRODUCER OF ANTHRAX ANTIGENS 2001
  • Mikshis N.I.
  • Popov Ju.A.
  • Drozdov I.G.
  • Kutyrev V.V.
 RU2180916C1
RECOMBINANT PLASMID DNA PRO PF5 DETERMINING SYNTHESIS OF CAPSULE ANTIGEN FI OF PLAGUE PATHOGEN AND PROTECTIVE ANTIGEN OF ANTHRAX PATHOGEN AND A METHOD OF CONSTRUCTION OF RECOMBINANT PLASMID DNA PRO PF5 1995
  • Alimov A.P.
  • Pavlov V.M.
 RU2110575C1
STABLE RECOMBINANT PROTECTIVE ANTIGEN FOR ANTHRAX VACCINE 2022
  • Granovskij Dmitrij Lvovich
  • Evtushenko Ekaterina Alekseevna
  • Ivanov Petr Alekseevich
  • Karpova Olga Vyacheslavovna
  • Kirpichnikov Mikhail Petrovich
  • Kondakova Olga Aleksandrovna
  • Nikitin Nikolaj Aleksandrovich
  • Ryabchevskaya Ekaterina Mikhajlovna
 RU2789418C1
ECOLI STRAIN - PRODUCER OF FULL-DIMENSIONAL PROTECTIVE BACILLUS ANTHRACIS ANTIGEN IN FORM OF VIRUS-LIKE PARTICLES 2016
  • Ivanov Pavel Aleksandrovich
  • Letarov Andrej Viktorovich
  • Kulikov Evgenij Evgenevich
  • Golomidova Alla Konstantinovna
  • Trifan Valerij Nikandrovich
  • Pozdnyakova Natalya Vladimirovna
  • Shibaeva Anna Valerevna
  • Biryukova Yuliya Konstantinovna
  • Kuznetsova Tatyana Vladimirovna
 RU2633504C1
STRAIN BACILLUS ANTHRACIS KM89 AS PRODUCER OF ANTHRAX ANTIGENS 2001
  • Mikshis N.I.
  • Popov Ju.A.
  • Drozdov I.G.
  • Kutyrev V.V.
  • Darmov I.V.
 RU2180349C1
STRAIN BACILLUS ANTHRACIS KM-90 AS BASE FOR GENETIC CONSTRUCTION OF PRODUCERS OF ANTHRAX ANTIGENS 2001
  • Mikshis N.I.
  • Popov Ju.A.
  • Drozdov I.G.
  • Kutyrev V.V.
 RU2180917C1

RU 2 321 628 C1

Authors

Mikshis Natal'Ja Ivanovna

Popov Jurij Alekseevich

Kudrjavtseva Ol'Ga Mikhajlovna

Dates

2008-04-10—Published

2006-06-26—Filed

download Download PDF read Similar patents