FIELD: biotechnology.
SUBSTANCE: invention relates to an artificial gene, allowing to express in bacteria cells an isolated domain 1 of PAG protective antigen from Bacillus anthracis 55 VNIIVVIM. This gene is intended for intriduction into the chromosome of bacillus in composition of specific DNA-structure.
EFFECT: invention allows to improve method of obtaining protective antigen of the anthrax pathogen Bacillus anthracis.
2 dwg, 3 ex
| Title | Year | Author | Number |
|---|---|---|---|
| E. COLI STRAIN - PRODUCER OF ISOLATED DOMAIN 1 OF PROTECTIVE BACILLUS ANTHRACIS ANTIGEN IN FORM OF VIRUS-LIKE PARTICLES | 2016 |
|
RU2633508C1 |
| ECOLI STRAIN - PRODUCER OF FULL-DIMENSIONAL PROTECTIVE BACILLUS ANTHRACIS ANTIGEN IN FORM OF VIRUS-LIKE PARTICLES | 2016 |
|
RU2633504C1 |
| RECOMBINANT STRAIN Bacillus anthracis STIΔTPA-1 (pUB110PA-1) AS PRODUCER OF ANTHRAX MICROORGANISM ANTIGEN | 2006 |
|
RU2321628C1 |
| ASPOROGENOUS RECOMBINANT STRAIN Bacillus anthracis 55ΔТПА-1Sро (pUB110РА-1) AS PRODUCER OF ANTHRAX MICROORGANISM ANTIGEN | 2006 |
|
RU2321629C1 |
| METHOD OF PRODUCTION OF PROTECTIVE ANTIGEN AND PROTEIN OF S-LAYER EA1OF ASPOROGENOUS RECOMBINANT STRAIN IN anthracis 55 ΔTPA-1Spo | 2012 |
|
RU2492241C1 |
| ATTENUATED STRAIN Bacillus anthracis FOR DEVELOPING MEANS OF SPECIFIC PREVENTION OF ANTHRAX | 2013 |
|
RU2544951C1 |
| STABLE RECOMBINANT PROTECTIVE ANTIGEN FOR ANTHRAX VACCINE | 2022 |
|
RU2789418C1 |
| METHOD OF DIFFERENTIATING BACILLUS ANTHRACIS FROM OTHER CLOSELY RELATED SPECIES OF GENUS BACILLUS BASED ON DETERMINING DIFFERENCES IN STRUCTURE OF CHROMOSOMAL GENES | 2013 |
|
RU2514663C2 |
| STRAIN BACILLUS ANTHRACIS KM-90 AS BASE FOR GENETIC CONSTRUCTION OF PRODUCERS OF ANTHRAX ANTIGENS | 2001 |
|
RU2180917C1 |
| STRAIN BACILLUS ANTHRACIS KM91 AS BASE FOR GENETIC CONSTRUCTION OF ANTHRAX ANTIGEN PRODUCERS | 2001 |
|
RU2180350C1 |
