FIELD: medicine, oncology, endocrinology, pharmacy.
SUBSTANCE: invention relates to an agent used in prophylaxis or treatment of patients suffering from anorexia and containing antibody raised against protein relates to the human parathyroid hormone (PTHrP) as an active component. Agent can comprise antibody raised against human PTHrP wherein antibody can represent human, humanized or chimeric one and shows the low antigenicity. Using the proposed agent provides improving a patient state suffering from malignant tumor.
EFFECT: valuable medicinal properties of agent.
6 cl, 6 tbl, 10 ex
Title |
Year |
Author |
Number |
H- AND L-CHAINS OF MONOCLONAL ANTIBODY PM-1 (MONAT) TO HUMAN IL-6R RECEPTOR AND THEIR V-REGION, MODIFIED MONAT, ITS H- AND L-CHAINS AND THEIR V-REGIONS, CDR-SEQUENCE, DNA-SEQUENCE |
1992 |
- Masajuki Tsutija
- Kokh Sato
- Mehri Margaret Bendig
- Stiven Tarran Dzhons
- Zhoze Uil'Jam Saldankha
|
RU2139351C1 |
RECONSTRUCTED HUMAN ANTI-HM 1,24 ANTIBODY, DNA ENCODING H- AND L-CHAIN OF HUMAN ANTI-HM 1,24 ANTIBODY, VECTOR, METHOD OF PREPARING RECONSTRUCTED HUMAN ANTI-HM 1,24 ANTIBODY, PHARMACEUTICAL COMPOSITION FOR MYELOMA TREATMENT |
1997 |
- Ono Kojtiro
- Okhtomo Tosikhiko
- Tsutija Masajuki
- Josimura Jasusi
- Kojsikhara Jasuo
- Kosaka Masaaki
|
RU2184147C2 |
HUMANIZED ANTIBODIES AND THEIR UTILIZATION |
1994 |
|
RU2139934C1 |
RECONSTRUCTED HUMAN ANTIBODIES SPECIFIC FOR INTERLEUKIN-8 |
1995 |
- Koudzi Matsusima
- Esikhiro Matsumoto
- Esiki Jamada
- Kokh Sato
- Masajuki Tsutija
- Tatsumi Jamazaki
|
RU2159776C2 |
PEPTIDE MPI WITHOUT SIGNAL SEQUENCE, DNA ENCODING THEREOF, VECTOR, METHOD FOR ASSAY CAPACITY FOR SECRETION OF TESTING PEPTIDE, METHOD FOR ISOLATING CDNA |
1998 |
- Kitamura Tosio
- Kodzima Tetsuo
|
RU2230751C2 |
DEGRADED ANTIBODY AS TPO AGONIST |
2001 |
- Tsutija Masajuki
- Okhtomo Tosikhiko
- Jabuta Naokhiro
- Tsunoda Khirojuki
- Orita Tetsuro
|
RU2287534C2 |
AGENT USED IN TREATMENT OF LYMPHATIC TISSUE TUMORS |
1998 |
- Koisikhara Jasuo
- Esimura Jasusi
|
RU2177805C2 |
MODIFIED ANTAGONISTIC ANTIBODY |
2001 |
- Fukusima Naosi
- Tsutija Masajuki
- Uno Sinsuke
- Okhtomo Tosikhiko
- Jabuta Naokhiro
- Tsunoda Khirojuki
|
RU2295537C2 |
RADIOACTIVE METAL-LABELLED ANTI-CADHERIN ANTIBODY |
2011 |
- Khino Akikhiro
- Nagano Akio
- Vatanabe Masakhiko
- Matsuura Tadasi
- Satokh Khirokazu
- Nomura Fumiko
- Mitomo Katsujuki
|
RU2577125C2 |
HUMAN IMMUNOGLOBULIN SHOWING SPECIFICITY TO HUMAN PROTEIN L-SELECTIN |
1993 |
|
RU2151612C1 |