FIELD: clinical immunology. SUBSTANCE: invention relates to humanized antibodies and their binding proteins capable of binding to T cells having specific variable beta-chains, in particular, to cell subpopulations expressing human Vβ 5.2 and/or 5.3 and Vβ 8.1. Invention further provides preparation of such antibodies and their therapeutic utilization. EFFECT: extended choice of autoimmune disease treatment drugs. 19 cl, 6 dwg, 13 ex
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