METHOD FOR EXTRACTION OF 1,3-PROPANEDIOL FROM ENZYMATIC BROTH Russian patent published in 2008 - IPC C07C31/20 C07C29/76 C02F1/26 

FIELD: organic chemistry, biotechnology.

SUBSTANCE: invention relates to variants of a method for extraction of 1,3-propanediol from enzymatic broth. The first variant involves steps for contacting enzymatic broth containing water, 1,3-propanediol and at least one impurity chosen from glycerol, glucose and butanetriol with at least one extractant chosen from alkanols, ketones, esters, acids, ethers or vegetable oils to form the first mixture. Then the first mixture is separated for the first phase and the second phase wherein the first phase comprises the greater part of extractant and at least some amount of 1,3-propanediol from enzymatic broth in the mass ratio 1,3-propanediol to at least one component taken from glycerol, glucose or butanetriol in the first phase above the mass ratio 1,3-propanediol and the same impurity in enzymatic broth before contacting enzymatic broth with the extractant wherein the second phase comprises the greater part of water and at least some amount of impurity from enzymatic broth followed by extraction of 1,3-propanediol by separation of the first phase from the second phase, contacting the first separated phase with aqueous solution to form the second mixture, and separation of the second mixture for the third and forth phases wherein the third phase comprises the greater part of the extractant from the first phase, and wherein the fourth phase comprises 1,3-propanediol and the greater part of the first amount of the first amount of aqueous solution, and wherein the mass ratio in the forth phase of 1,3-propanediol to any presenting mixture is more as compared with the mass ratio of 1,3-propanediol to the same impurity in the enzymatic broth being before contacting the enzymatic broth with the extractant, and extraction of 1,3-propanediol, and separating the fourth phase from the third phase. Invention provides enhancing purity of 1,3-propanediol.

EFFECT: improved method of extraction.

30 cl, 15 tbl, 9 dwg, 10 ex