FIELD: chemical technology.
SUBSTANCE: invention relates to a method for synthesis of acetylene-unsaturated alcohol used in synthesis of vitamins and carotinoids. Method involves reaction of carbonyl compound with acetylene in the presence of ammonia and alkaline metal hydroxide wherein carbonyl compound represents methylethyl ketone, methylglyoxal dimethylacetal, 6-methyl-5-heptene-2-one, 6-methyl-5-octene-2-one, hexahydropseudoionone, 4-(2,6,6-trimethyl-1-cyclohexen-1-yl)-3-butene-2-one or 6,10,14-trimethyl-2-pentadecanone. Alkaline metal hydroxide is used in an aqueous solution wherein the molar ratio between this alkaline metal hydroxide and carbonyl compound is less 1:200. Method provides preparing acetylene-unsaturated alcohol with the high yield for the short reaction period.
EFFECT: improved method of synthesis.
11 cl, 5 tbl, 5 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR PREPARING ACETYLENIC ALCOHOLS USING CONTINUOUS PROCESS | 1999 |
|
RU2216532C2 |
| METHOD FOR PREPARING α-ACETYLENE γ-DIOLS | 2001 |
|
RU2206559C1 |
| METHOD FOR PRODUCTION OF 1,2A-DIMETHYL-4E-ETHYNYL-TRANS-DECAHYDROQUINOLONE 4A AND ITS SALTS | 1992 |
|
RU2054419C1 |
| METHOD OF OBTAINING CARBOXYLIC ACID AMIDE FROM CARBONYL COMPOUND AND HYDROCYANIC ACID | 2009 |
|
RU2552619C9 |
| PROCESS OF PRODUCTION OF TERTIARY ALPHA-ACETYLENE DIOLS | 2001 |
|
RU2199519C2 |
| METHOD OF PRODUCING 1-PHENYL PROPARGYL ALCOHOL | 2012 |
|
RU2515241C1 |
| 0 |
|
SU422134A3 | |
| METHOD OF PRODUCING ALKYLARYL(HETARYL)ETHYNYL CARBINOLS | 2012 |
|
RU2479565C1 |
| METHOD FOR SYNTHESIS OF ALKYL(METH)ACRYLATES | 2006 |
|
RU2409552C2 |
