FIELD: organic chemistry, chemical technology.
SUBSTANCE: invention relates to chemistry of triterpenoid esters of lupane group, namely, to a method for synthesis of novel compounds representing 3β,28-di-O,O'-aroylacetate- and 3β,28-di-O,O'-aroylpyruvates of betulin of the formula (I): 
wherein Ar means C6H5, p-CH3C6H4, p-C2H5O-C6H4; n = 0, 1 possessing analgesic activity. Method involves interaction of 5-aryl-2,3-dihydrofuran-2,3-diones with betulin at heating in toluene medium at temperature 60-70°C for 5-6 h, or at boiling in toluene for 25-30 min, respectively. Invention provides a simple synthesis of novel active compounds from available raw as potential drugs that is not described in special literature.
EFFECT: improved method of synthesis.
3 cl, 1 tbl, 7 ex
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