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IPC

A61K31/704(2006-01-01)

A61K31/675(2006-01-01)

A61K31/7068(2006-01-01)

A61P35/00(2006-01-01)

(21) (22)

Application

2006121303/14, 2006-06-15

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Start date

2006-06-15

(22)

Actual filing date

2006-06-15

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Published

2008-06-10

(72)

Inventor

Krasulina Natal'Ja Anatol'EvnaSlonimskaja Elena MikhajlovnaGarbukov Evgenij Jur'EvichDoroshenko Artem Vasil'EvichKokorina Julija Leonidovna

(73)

Holder

Gosudarstvennoe Uchrezhdenie Nauchno-Issledovatel'Skij Institut Onkologii Tomskogo Nauchnogo Tsentra Sibirskogo Otdelenija Rossijskoj Akademii Meditsinskikh Nauk Nii Onkologii Tnts So Ramn)

METHOD OF OPERABLE BREAST CANCER MEDICAL TREATMENT Russian patent published in 2008 - IPC A61K31/704 A61K31/675 A61K31/7068 A61P35/00 

Abstract RU 2325914 C2

FIELD: medicine; carcinology.

SUBSTANCE: method includes 2-4 presurgical chemotherapy courses within 14 days implying intravenous injections of adriamycin of daily dose 30 mg/m in 1st and 8th day and intramuscular injections of cyclophosphan of daily dose 100 mg/m2 during 14 days. Intervals between courses are 28 days. In addition course implies oral introduction of xeloda of daily dose 2000 mg/m2 twice a day. Method ensures reduction of total chemotherapy toxicity owing to selective activation of medicines directly inside of tumour tissue, and makes possible to perform organ preserving surgical treatment.

EFFECT: reduction of total chemotherapy toxicity; organ preserving surgical treatment.

3 ex

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RU 2 325 914 C2

Authors

Krasulina Natal'Ja Anatol'Evna

Slonimskaja Elena Mikhajlovna

Garbukov Evgenij Jur'Evich

Doroshenko Artem Vasil'Evich

Kokorina Julija Leonidovna

Dates

2008-06-10—Published

2006-06-15—Filed

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