FIELD: chemistry.
SUBSTANCE: invention proposes a 2,3-dihydro-6-nitroamidazo[2,1-b]oxazole derivative, with the following general formula (1) , where R1 represents a hydrogen atom or a C1-6alkene group, n is an integer from 0 to 6, R2 represents a OR3 group or similar, and R3 represents a hydrogen atom, C1-6alkene group or similar. R1 and -(CH2)nR2 can be interlinked with adjacent carbon atoms through nitrogen atoms, with formation of a spiro-ring, represented by general formula (H) , where R41 represents a hydrogen atom, C1-6alkene group or similar.
EFFECT: given compound has bactericidal action against Mycobacterium tuberculosis, multi-resistant to medication for Mycobacterium tuberculosis and atypical acid-fast bacteria.
48 cl, 119 tbl, 1885 ex
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Authors
Dates
2008-06-10—Published
2003-10-10—Filed