DERIVATIVE OF 4,4-DIFLUORO-1,2,2,4-TETRAHYDRO-5H-1-BENZAZEPINE AND ITS SALT Russian patent published in 2008 - IPC C07D223/16 C07D401/12 A61K31/55 A61P13/02 

FIELD: chemistry.

SUBSTANCE: 4,4-diphtor-1,2,3,4-tetrahydro-5H-1-benzazepine derivative of the formula (I) or its pharmaceutically acceptable salt are described , the signs of the formula stand for the following R¹: amines, which can be substituted, -OH or O-low alkyl; R²: CF₃ or halogen, R³: H or halogen, a, b: each of them has ordinary link or olefinic link, notably that one has ordinary link and the other - olefinic link, X-: (1) -CH=CH-, Y; (1) CH or N, in the case when a has ordinary link and b - olefinic link, -A-: -O-, -S-, -NH or N (low alkyl), and B: low alkyl, low alkenyl, low alkynyl, cycloakyl or aryl, each of them can be substituted. The pharmaceutical composition of agonist V₂ receptor arginine-vasopressin, which includes the compound of the formula I as an active ingredient is described.

EFFECT: new compound has effective, biological properties.

36 tbl