FIELD: chemistry.
SUBSTANCE: invention refers to the method of preparation of 3-halogen-4.5-dihydro-1H-pyrasol compound of the formula , it includes interreaction with HX1of other 4.5-dihydro-1H-pyrasol compound of the formula , in which X1 is halogen and R3, R4, Z, n and X2 have values given in the description. The invention also describes preparation of the compounds of the formula , in which X1, R3, R6, R7, R8a, R8b and n have values, which are indicated in the description, in terms of the formula (Ia) of the compound, prepared according to p.1 of the invention formula.
EFFECT: development of the alternative method of preparation of the compounds with using reagent of relatively low price.
9 cl, 1 tbl, 4 ex, 9 dwg
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Authors
Dates
2008-06-20—Published
2003-07-29—Filed