CONVERSION OF 2-PYRAZOLINES TO PYRAZOLES USING BROMINE Russian patent published in 2011 - IPC C07D401/04 C07D231/16 C07D231/06

Abstract RU 2410381 C2

FIELD: chemistry.

SUBSTANCE: invention relates to a method of producing a compound of formula 1a, where X denotes a halogen or C₁-C₄halogenalkyl; Z denotes N or CR⁹; each R⁵ independently denotes halogen or C₁-C₄halogenalkyl; R⁹ denotes H, halogen or C₁-C₄halogenalkyl; R¹⁰ denotes H or C₁-C₄alkyl; and n is an integer from 0 to 3, involving bringing 2-pyrazoline of formula 2a, where X, Z, R⁵, R⁹, R¹⁰ and n assume values given above, into contact with bromine in a medium of a suitable inert organic solvent at temperature 80-180°C.

EFFECT: obtaining pyrazoles of formula 1a with high output and purity.

7 cl, 2 tbl, 3 ex

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RU 2 410 381 C2

Authors

Fagan Pol Dzhozef

Dates

2011-01-27—Published

2006-03-14—Filed