METHOD OF ERYTHROCYTES OSMORESISTIVITY EVALUATION Russian patent published in 2008 - IPC G01N33/49 

FIELD: medicine; laboratory diagnostics.

SUBSTANCE: method includes blood testing for quantification of haemolysis severity in sodium chloride solution of various concentrations. This implies analysis of three capillary blood samples for supernatant optical density: with distilled water, 0.9% sodium chloride solution and 0.45% sodium chloride solution using spectrophotometer at wave length 414 nm in dish of absorption length 1 cm against distilled water. Haemolysis severity is evaluated on basis of original physiological physical-chemical composition of erythrocyte membranes in 0.9% sodium chloride solution and osmotic stress testing in 0.45% sodium chloride solution compared to haemolysis severity in distilled water testing which is considered to be 100%. Haemolysis severity values, 1.61±0.23% tested in 0.9% sodium chloride solution and 25.16±1.83% tested in 0.45% sodium chloride solution erythrocytes osmoresistivity is interpreted as normal.

EFFECT: haemolytic state screening.

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