METHOD OF EXPRESS-DIAGNOSTICS OF POISONING WITH HEMOLYTIC POISONS Russian patent published in 2013 - IPC A61B10/00 G01N33/48 

FIELD: medicine.

SUBSTANCE: invention relates to field of medicine, namely to toxicology and clinical laboratory diagnostics. In order to carry out express-diagnostics of poisoning with hemolytic poisons, analysis of plasma of peripheral, including capillary, blood is performed. With application of 0.005-0.01% solution of sodium dodecylsulfate in blood plasma sample all hemoglobin fractions are transformed for several seconds with ratio sample:reagent 1:10. After that, sample is photometrically scanned at wavelengths 540 and 700 nm, and concentration of ectoglobular hemoglobin is calculated. If value of ectoglobular hemoglobin is higher than 1.0 g/l, poisoning with hemolytic poisons is diagnosed.

EFFECT: method eliminates poisonous component from reagent composition, reduces time of analysis duration, reduces interference of sample components, minimises quantity of biomaterial required for test, increases diagnostics efficiency.

1 dwg, 4 tbl, 2 ex