APPLICATION OF BRADYKININ-B2 RECEPTORS ANTAGONISTS FOR OSTEOARTHROSIS TREATMENT Russian patent published in 2008 - IPC A61K38/04 A61P19/02 

Abstract RU 2329057 C2

FIELD: medicine.

SUBSTANCE: invention refers to application of peptides of antagonistic action in the relation bradykinin, suitable for medical products for prevention and treatment of diseases influenced by increased activity of matrix metalloproteinase. They are degenerative arthropathies, e.g., osteoarthrosis, spondylosis, as well as cartilage atrophy caused by joit injury or prolonged joint immovability following meniscus or patella damage or ligamentous rupture.

EFFECT: invention provides more effective brake of matrix splitting in comparison with only MMP inhibition of already released or formed tissues.

3 cl, 1 tbl

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RU 2 329 057 C2

Authors

Mikhaehlis Martin

Rudol'Fi Karl

Dates

2008-07-20Published

2004-01-23Filed