PHARMACEUTICAL COMPOSITION CONTAINING N-[(1-BUTYL-4-PIPERIDINYL) METHYL]-3,4-DIHYDRO-2N-[1,3]OXAZINO[3,2-a]INDOLE-10- CARBOXAMIDE OR ITS SALT, AND RELATED PRODUCTION METHOD INCLUDING AIR-STREAM GRANULATION Russian patent published in 2008 - IPC A61K9/16 A61K9/20 A61K31/5365 

FIELD: medicine, pharmaceutics.

SUBSTANCE: present invention refers to chemical-pharmaceutical industry and concerns method of production of pharmaceutical composition containing N[(1-butyl-4-piperidinyl) methyl]-3,4-dihydro-2n -[1,3]oxazino[3,2]indole-10-carboxamide (SB 207266) piboserod or its pharmaceutically acceptable salt in combination with one or more pharmaceutically acceptable excipients, thus method includes formation of part or whole SB 207266 or its salts in granules by air-stream granulation. In invention there is also pharmaceutical composition offered which can be produced by air-stream granulation and/or which is produced by air-stream granulation. Declared invention enables to improve parameters of finished composition, and also to scale manufacture.

EFFECT: reception of a pharmaceutical composition with the improved parameters and possibility of its scale production process.

75 cl, 16 ex, 2 tbl, 4 dwg