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2 330 034

(13)

(51)

IPC

C07D409/06(2006-01-01)

A61K31/4535(2006-01-01)

A61P11/06(2006-01-01)

A61P19/02(2006-01-01)

A61P17/00(2006-01-01)

A61P27/02(2006-01-01)

(21) (22)

Application

2006137717/04, 2005-03-24

(24)

Start date

2005-03-24

(22)

Actual filing date

2005-03-24

(45)

Published

2008-07-27

(72)

Inventor

Gao ChzhunliDehvis LarriLevell DzhulianChekaj MarkSledeski Adam V.Addad Ehl'-Bdaui

(73)

Holder

Aventis Farmas'Jutikalz Ink.

[4-(5-AMINOMETHYL-2-FLOUROPHENYL)-PYPERIDIN-1-YL]-(4-BROMINE-3-PROPOXYTHIOPHENE-2-YL)-METHALON HYDROCHLORIDE AS INHIBITOR OF MAST CELLS TRYPTASE Russian patent published in 2008 - IPC C07D409/06 A61K31/4535 A61P11/06 A61P19/02 A61P17/00 A61P27/02

Abstract RU 2330034 C1

FIELD: chemistry.

SUBSTANCE: described are the bonds of the formula of pharmaceutical acceptable salt. The bonds possess an inhibiting action in the relation to beta-tryptase. Also, described is the method to treat patients suffering or subject to physiological diseases, with which it is necessary to increase the level of the inhibitor of tryptase.

EFFECT: bonds increase the level of the inhibitor of tryptase.

13 cl, 3 ex, 2 dwg

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RU 2 330 034 C1

Authors

Gao Chzhunli

Dehvis Larri

Levell Dzhulian

Chekaj Mark

Sledeski Adam V.

Addad Ehl'-Bdaui

Dates

2008-07-27—Published

2005-03-24—Filed