FIELD: chemistry.
SUBSTANCE: invented group pertains to biotechnologies; in particular, to the method of obtaining macrolide compound 11107D with formula (II) and to Streptomyces sp. FERM BP-8551, Mortierella sp. FERM BP-8547, Mortierella sp. FERM BP-8548 and Micromonosporaceae FERM BP-8550 strains. The initial compound 11107B with formula (I) undergoes biotransformation to the target compound with formula (II) through incubation in the presence of a strain, capable of converting macrolide compound 11107B into 11107D substance and a Mortierella, Streptomyces type or Micromonosporaceae family, or a mycelium cultivated strain sample. The target substance 11107D is separated from the reaction medium.
EFFECT: increased anti-tumour activity and stability of the compound.
8 cl, 9 tbl, 10 ex
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