METHOD OF OBTAINING 2-CYAN-3-HYDROXY-N-(PHENYL)BUTH-2-ENAMIDES Russian patent published in 2008 - IPC C07C253/30 C07C255/42 

Abstract RU 2330838 C2

FIELD: chemistry.

SUBSTANCE: invention concerns obtaining a compound of the formula I , where R1 is -CF3, and R2 is a hydrogen atom. The method involves introduction of a compound of the formula II , where R1 and R2 are the same as above, into at least one solvent, and obtained solution or suspension is cooled down and mixed with water solution of at least one base from the group of alkali metal hydroxides, such as sodium or potassium hydroxide in solid or alkali form, amides such as sodium amide, alkoholates such as sodium ethylate or potassium tert-butylate, metalorganic compounds such as n-butyllium, or a mixture of bases, in the presence of acetic anhydride, followed by extraction of the obtained coumpound of the formula I.

EFFECT: reduction of reaction length and increase in output.

6 cl, 2 tbl, 16 ex

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RU 2 330 838 C2

Authors

Khakhtel' Jokhen

Najzes Bernd

Shvab Vil'Frid

Utts Roland

Tsan Martin

Dates

2008-08-10Published

2004-03-06Filed