MODULATORS OF ATP-BINDING TRANSPORTERS Russian patent published in 2015 - IPC C07D215/56 C07D401/12 C07D405/12 C07D409/12 C07D413/12 C07D417/12 C07D471/08 A61K31/4709 A61K31/4427 A61K31/404 A61P11/00 

Abstract RU 2552353 C2

FIELD: medicine.

SUBSTANCE: invention relates to a method of treatment or relieving the severity of cystic fibrosis in a patient, where the patient has the cystic fibrosis transmembrane receptor (CFTR) with R117H mutation, including a stage of introduction to the said patient of an effective quantity of N-(5-hydroxy-2,4-ditert-butyl-phenyl)-N-methyl-4-oxo-1H-quinoline-3-carboxamide.

EFFECT: elaborated is the method of treating cystic fibrosis, based on the application of N-(5-hydroxy-2,4-ditert-butyl-phenyl)-N-methyl-4-oxo-1H-quinoline-3-carboxamide.

3 cl, 4 tbl, 30 ex

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RU 2 552 353 C2

Authors

Shet Urvi

Fehnning Lev T. D.

Numa Mekhdi

Binch Khehjli

Kharli Dennis Dzhejms

Chzhou Tszinlan'

Adida Rua Sara S.

Khejzlvud Anna R.

Silina Alina

Vairagoundar Radzhendran

Van Gur Frederik F.

Grotenkhejs Peter Diderik Jan

Botfild Martin K.

Dates

2015-06-10Published

2010-12-10Filed