FIELD: chemistry.
SUBSTANCE: invention concerns a method of obtaining new condensed amino-1,3,5-triazines with gem-dimethyl group of the formula , where X-N-C=Y
where R=H, R1=Me; R=Me, R1=H;
where R=Ph, 3-pyridile, 4-pyridile. The method involves interaction of azaheterylguanidine of the formula
with acetone in the presence of a catalyst, followed by extraction of the target products.
EFFECT: antifolate effect of the obtained compounds allowing their application as medicine.
3 cl, 4 ex
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Authors
Dates
2008-08-10—Published
2006-03-15—Filed