PHARMACEUTICAL COMPOSITIONS AND METHODS, THAT INCLUDE COMBINATIONS OF 2-ALKYLDIEN-19-NOR-VITAMIN D DERIVATIVES AND ESTROGENS AGONIST/ANTAGONIST Russian patent published in 2008 - IPC A61K31/593 A61K31/40 A61K45/00 A61P19/10 

Abstract RU 2331425 C2

FIELD: medicine, pharmacology.

SUBSTANCE: invention relates to pharmaceutical composition for senile osteoporosis, post-menopausal osteoporosis, bone fractures, bone transplant, and osteopenia or male osteoporosis treatment, that include effective therapeutic quantity, in amount 0.01 mcg/kg/day to 10 mcg/kg/day of compound 2-methylene-19-nor-20(S)-1α,25-dihydroxyvitamin D3, and effective therapeutic quantity, in amount 0.01 mcg/kg/day to 200 mcg/kg/day of selective estrogen receptor modulator, which bounds to estrogen receptor; the selective estrogen receptor modulator mentioned being chosen from the group comprising estrogen agonist, estrogen antagonist, or its pharmaceutically acceptable salt.

EFFECT: efficiency of medication is increased.

6 cl, 2 tbl, 1 ex

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RU 2 331 425 C2

Authors

Li Ehndrju Dzhordzh

Dates

2008-08-20Published

2004-09-06Filed