FIELD: medicinal preparations. SUBSTANCE: pharmaceutical composition contains agonists/antagonists of estrogen and prostaglandins or agonists/antagonists of prostaglandin. The invention also deals with sets of said compositions for treatment of osseous disturbances, including osteoporosis. The composition increases (preserves) osseous mass, and, as a result, osteoporosis is prevented, decelerated and/or regressed as well as related osseous disturbances. EFFECT: higher efficiency. 33 cl
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