INHIBITORS OF ANTIGEN PRESENTATION BY II CLASS MHC MOLECULES AND METHODS OF APPLICATION THEREOF Russian patent published in 2008 - IPC C07K7/08 C07K7/06 A61K38/08 A61K38/10 A61P37/00 

Abstract RU 2333219 C2

FIELD: chemistry.

SUBSTANCE: invention concerns biologically active compounds with inhibition effect on binding antigen with II class MHC molecules, particularly with II class MHC molecule HLA-DR2. Also, the invention proposes pharmaceutical compositions containing such compounds, and their application in obtaining medications for treatment or prevention of diseases connected to T-cell proliferation, such as autoimmune diseases and disorders of inhibition of binding II class MHC molecule HLA-DR2.

EFFECT: obtaining pharmaceutical composition for treatment or prevention of diseases connected with T-cell proliferation.

17 cl, 4 tbl, 6 ex

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RU 2 333 219 C2

Authors

Olson Gehri L.

Kuk Charl'Z M.

Self Kristofer R.

Dates

2008-09-10Published

2004-02-13Filed