FIELD: medicine.
SUBSTANCE: device includes core containing at least one pharmaceutically active agent. Core is made from elastomeric composition selected from the group consisting of poly(dimethylsiloxane), siloxane-based elastomer including 3,3,3-trifluoropropyl groups attached to Si atom of siloxane units, siloxane-based elastomer, which includes poly(alkyleneoxide) groups, and their mixtures. The said core is encased by membrane. Membrane is made from the same elastomeric composition as core. Pharmaceutically active agent is selected from the group, which includes anti-allergic agents, anti-infection agents, anti-asthmatic agents, anti-inflammatory agents, anti-virus agents, anti-bacterial agents, anti-histamine means, anti-fungal agents, anesthetics, opioids, vasorelaxants, muscarinic agents, sympathomimetics, corticosteroids and their mixtures. Delivering device, according to invention, for nasal or otological application ensures preliminary set, constant rates of release of one or more pharmaceutically active agents.
EFFECT: device is safe and does not cause discomfort to patients.
8 cl, 6 dwg, 1 tbl, 5 ex
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Authors
Dates
2008-09-27—Published
2004-01-14—Filed