FIELD: chemistry.
SUBSTANCE: invention refers to production of water-soluble associative carboxymethylcellulose (CMC) which exhibits unique and very highly favourable rheological properties and performance attributes, and can be used in food industry, pharmaceutical industry, for individual products, paper, building and engineering structural materials, at oil fields and other sectors of the national economy. Carboxymethylcellulose (CMC), has relative viscosity ratio CMC in 6M urea and relative viscosity ratio CMC in water less than 0.9. Method of CMC production includes a) reaction in suspension process of cellulose source and NaOH in amount approximately 50-80 mass % of stoichiometric amount within time period and at temperature sufficient enough to produce alkaline cellulose; b) reduction of total alkali to approximately stoichiometric level and addition of chloroacetic acids in sufficient amount, and suspension reaction at temperature and during time, sufficient for etherification resulted in specified CMC product. The pharmaceutical composition contains solid dosage of the specified product form as binder or coating and additionally pharmaceutically active component.
EFFECT: production of water-soluble associative carboxymethylcellulose (CMC) which exhibits unique and very highly favourable rheological properties and performance attributes.
30 cl, 7 dwg, 3 tbl, 19 ex
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Authors
Dates
2008-09-27—Published
2003-11-26—Filed