METHOD OF OBTAINING COMPOSITIONS INCLUDING HEAT SHOCK PROTEINS OR ALPHA-2-MACROGLOBULIN, SUITABLE FOR TREATMENT OF MALIGNANT TUMOUR AND INFECTIOUS DISEASE Russian patent published in 2008 - IPC A61K38/16 A61K39/00 

FIELD: medicine.

SUBSTANCE: group of inventions concerns methods and compositions for preventive maintenance and treatment of infectious diseases and malignant tumours. The method of obtaining the complexes containing of one or more heat shock proteins, bound in a complex with the antigenic peptides is offered, providing populations engagement of antigenic peptides from one or more various heat shock proteins in vitro in conditions, where the specified peptides form a complex with the specified heat shock proteins, where population of antigenic peptides contains at least 50 various peptides and is obtained by the way including splitting of an albuminous preparation by one or more proteinases or splitting of an albuminous preparation by means of one or not more enzymatic methods where the specified albuminous preparation occurs from antigenic cells or their cellular fraction and includes at least 50 % of various proteins or at least 50 various proteins of the specified antigenic cells or cellular fraction accordingly. The composition containing immunogenic quantity of complexes, containing heat shock proteins in a complex with antigenic peptides is offered. The provocation method of the immune response at the person against the second antigenic cell is offered, the way of treatment or prevention of a malignant tumour Is offered. The way of treatment or the infectious disease prevention is offered.

EFFECT: obtaining of compositions for prevention and treatment of infectious diseases and malignant tumours.

65 cl, 1 tbl