FIELD: medicine.
SUBSTANCE: invention concerns medicine, namely oncology and can be used in treatment of tumours. The method involves introduction of an autologous vaccine representing heat-shock proteins recovered from tumour tissue of the patient in a complex with tumour antigens. Thus treatment with the autologous vaccine is preceded with introduction of an oncolytic attenuated Newcastle disease virus as an adjuvant.
EFFECT: application of the invention allows improving clinical effectiveness in tumours ensured by formation of a vaccine-induced specific immune response against tumour and additional stimulation of nonspecific immunity combined with cytolytic activity of the adjuvant.
2 cl, 4 dwg, 4 ex
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Authors
Dates
2010-01-20—Published
2008-04-30—Filed