FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to biotechnology and concerns the use of lectin or lectin-like molecules for glycoproteids and antigenic molecules oligomerisation activation. Substance of the invention involves a composition presented by one or more noncovalent complexes eliciting an immune response in a patient where each complex contains heat shock protein, antigenic molecule and lectin, and where heat shock protein is glycolised, and where heat shock protein and antigenic molecule are originated from tumour tissue. There also presented methods of manufacturing of such molecular complexes and methods of using the compositions including such molecular complexes for prevention and treatment of cancer and infectious diseases.
EFFECT: advantage of the invention consists in increase in activity.
34 cl, 9 ex, 2 tbl, 13 dwg
Title | Year | Author | Number |
---|---|---|---|
APPLICATION OF HEAT SHOCK PROTEINS FOR IMPROVEMENT OF THERAPEUTICAL EFFECT OF NON-VACCINAL MEDICINAL EFFECT | 2003 |
|
RU2376029C2 |
USING HEAT SHOCK PROTEINS FOR IMPROVING THERAPEUTIC EFFECT OF NON-VACCINE THERAPEUTIC INTERVENTION | 2009 |
|
RU2573380C2 |
METHOD OF OBTAINING COMPOSITIONS INCLUDING HEAT SHOCK PROTEINS OR ALPHA-2-MACROGLOBULIN, SUITABLE FOR TREATMENT OF MALIGNANT TUMOUR AND INFECTIOUS DISEASE | 2002 |
|
RU2335295C2 |
APPLICATION OF HEAT-SHOCK PROTEINS FOR IMPROVING EFFECTIVENESS OF ANTIBODY THERAPIES | 2003 |
|
RU2375077C2 |
METHOD FOR BIOLOGICAL MATERIAL OBTAINING FOR CREATION OF AUTOLOGICAL ANTITUMOUR VACCINES | 2016 |
|
RU2640017C1 |
PROTEIN-PEPTIDE ANTITUMOR COMPOSITION, CELL PREPARATION ACTIVATED THEREWITH AND METHOD FOR TUMOR PROPHYLAXIS OR TREATMENT | 2004 |
|
RU2283129C1 |
METHOD OF TREATING ONCOLOGICAL DISEASES | 2008 |
|
RU2379055C1 |
COMPOSITIONS AND METHODS FOR USING CA9 PROTEIN FOR IMMUNE SYSTEM STIMULATION | 2008 |
|
RU2497543C2 |
VACCINE COMPOSITION FOR PROPHYLAXIS AND TREATMENT OF TUMOR DISEASES, RECOMBINANT PLASMID DNA PROVIDING HYBRID PROTEIN SYNTHESIS AND METHOD FOR PRODUCTION THEREOF | 2006 |
|
RU2316342C1 |
VACCINE COMPOSITIONS, METHODS FOR APPLICATION THEREOF IN MELANOMA PREVENTION AND TREATMENT, AND GENETIC CONSTRUCTIONS FOR OBTAINING ACTIVE SUBSTANCES OF COMPOSITION | 2006 |
|
RU2333767C2 |
Authors
Dates
2010-09-20—Published
2004-02-27—Filed