FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions refers to medicine, namely immunology and may be used for immune system stimulation. That is ensured by administering a composition containing a complex of isolated carbonic anhydrase IX (CA9) protein and an antigen, wherein the isolated CA9 proteins and the antigen are noncovalently linked to each other, into an individual. The group of inventions also refers to a composition containing a purified population of dendrite cells coming into contact with the above composition.
EFFECT: group of inventions provides immune cell stimulation by enhancing the antigen immunogenicity ensured by adding the complex with the CA9 protein which can function as a chaperone protein.
18 cl, 6 dwg, 8 ex
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| VECTOR, CO-EXPRESSING MOLECULES FOR VACCINATION AND COSTIMULATORY MOLECULES | 2016 |
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RU2748378C2 |
