FIELD: chemistry, medicine.
SUBSTANCE: invention relates to derivatives of 4-pyrrolidine phenyl benzole ether of formula 
where X-Y stands for -CH2-O-; R1, R1.1 and R1.2 independently on each other are selected from group, including H, haloid, haloid (C1-C6)alkyl, R21, R22 and R23 independently on each other stand for H; R24 stands for H; R3 stands for H; R4 stands for -CONHR5, -CN or -NHR6; R5 stands for H, (C1-C6)alkyl; R6 stands for -CO-H, -CO-(C1-C6)alkyl, -CO-NH2, -SO2-(C1-C6)alkyl; as well as its individual isomers and racemic and non-racemic mixtures. Compounds 1 inhibit monoaminooxidase B, which allows to apply them in pharmaceutical composition and for production of medications, intended for treatment and prevention of Alzheimer's disease and senile dementia.
EFFECT: invention ensures enhancing efficiency of composition and method of treatment.
15 cl, 7 dwg, 21 ex
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