FIELD: medicine; pharmacology.
SUBSTANCE: present group of inventions is referred to biologically active compounds characterised by the formula (I), their pharmaceutically acceptable salts, solvates and stereoisomers, the pharmaceutical compositions containing specified compounds, method of obtaining, the intermediate compounds used for obtaining of compounds of the formula (I), and methods of treatment of the painful conditions mediated by muscarine receptors with use of specified compounds 
where R4 represents hydrogen; R5 is chosen from C1-6alkyl, C3-6cycloalkyl and -CH2-R8; where the alkyle group is unessentially replaced by or 1-5 fluorine-substituents; R8 is chosen from C3-6cycloalkyl or phenyl; a, b and with are 0; d is 1; e is 8 or 9.
EFFECT: obtaining of new biologically active compounds for treatment of some diseases.
10 cl, 27 ex, 15 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| QUATERNARY AMMONIUM DIPHENYLMETHYL COMPOUNDS USED AS MUSCARINIC RECEPTOR ANTAGONISTS | 2008 |
|
RU2452728C2 |
| GUANIDINE-CONTAINING COMPOUNDS APPLICABLE AS MUSCARINIC RECEPTOR ANTAGONISTS | 2008 |
|
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| BIPHENYL COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | 2005 |
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| BIPHENYL DERIVATIVES | 2004 |
|
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| PYRROLIDINIUM DERIVATIVES AS M3 MUSCARINIC RECEPTORS | 2005 |
|
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| DERIVATIVES OF 4-PIPERIDINYLALKYLAMINE AND PHARMACEUTICAL COMPOSITION POSSESSING ANTAGONISTIC AFFECT ON MUSCARINIC RECEPTOR | 2002 |
|
RU2300524C2 |
| DERIVANTS OF BICYCLO[2, 2, 1] HEPT-7-YLAMINE AND THEIR APPLICATIONS | 2006 |
|
RU2442771C2 |
| COMPOSITIONS AND METHODS FOR TREATING COGNITIVE DISORDERS | 2005 |
|
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| PIPERAZINYL PYRIMIDINE DERIVATIVES, PREPARATION METHOD AND USE THEREOF | 2013 |
|
RU2608315C2 |
| SUBSTITUTED 1-AMINOALKYL LACTAMS, PHARMACEUTICAL COMPOSITION BASED ON THEREOF AND METHOD FOR THEIR PREPARING | 2001 |
|
RU2243222C2 |
